Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 4/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22080250 | 0.80 | MEN1 (0.42) | MEN1MAPK1KMT2AAPLNRCTSK | |
| SCHEMBL13360948 | 0.78 | KMT2A (0.41) | MEN1MAPK1KMT2ACTSKHDAC4 | |
| SCHEMBL22644381 | 0.77 | MEN1 (0.38) | MEN1MAPK1KMT2AAPLNRCTSK | |
| SCHEMBL13415253 | 0.75 | KMT2A (0.38) | MEN1MAPK1KMT2AAPLNRCTSK | |
| SCHEMBL3345289 | 0.75 | KMT2A (0.38) | MEN1MAPK1KMT2AAPLNRCTSK | |
| SCHEMBL634842 | 0.75 | KMT2A (0.38) | MEN1MAPK1KMT2AAPLNRCTSK | |
| SCHEMBL8372247 | 0.75 | MEN1 (0.38) | MEN1MAPK1KMT2ACTSKHDAC4 | |
| SCHEMBL13302345 | 0.75 | MEN1 (0.38) | MEN1MAPK1KMT2ACTSKHDAC4 | |
| SCHEMBL13360863 | 0.75 | KMT2A (0.38) | MEN1MAPK1KMT2AAPLNRCTSK | |
| SCHEMBL20107170 | 0.75 | KMT2A (0.38) | MEN1MAPK1KMT2AAPLNRCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086995-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-02-22 | — | — | EP | disclosed |
| WO-2008064066-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-29 | — | — | WO | disclosed |