Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272147 | 0.86 | NAAA (0.39) | NAAAEPHX1EPHX2HTTALDH1A1 | |
| SCHEMBL3240877 | 0.83 | NAAA (0.41) | NAAAEPHX1HTTAKT1AKT2 | |
| SCHEMBL11590153 | 0.81 | NAAA (0.58) | NAAAEPHX1EPHX2HTTALDH1A1 | |
| SCHEMBL11590755 | 0.81 | NAAA (0.58) | NAAAEPHX1EPHX2HTTALDH1A1 | |
| SCHEMBL4350675 | 0.81 | NAAA (0.58) | NAAAEPHX1EPHX2HTTALDH1A1 | |
| SCHEMBL11592192 | 0.81 | NAAA (0.58) | NAAAEPHX1EPHX2HTTALDH1A1 | |
| SCHEMBL4310566 | 0.80 | NAAA (0.61) | NAAAEPHX1EPHX2HTTALDH1A1 | |
| SCHEMBL4343264 | 0.80 | NAAA (0.57) | NAAAEPHX1EPHX2HTTALDH1A1 | |
| SCHEMBL8630971 | 0.80 | NAAA (0.56) | NAAAEPHX1EPHX2HTTALDH1A1 | |
| SCHEMBL451499 | 0.80 | NAAA (0.56) | NAAAEPHX1EPHX2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093722-A | ADMINISTERING AN ANTICANCER DRUG N-3-OXO-4-AZA-5 ALPHA-ANDROST-1-ENE-17 BETA-CARBOXAMIDE, A TESTOSTERONE 5-ALPHA REDUCTASE ENZYME INHIBITOR | SANKYO COMPANY, LIMITED (JP) | 2000-07-25 | — | — | US | disclosed |