Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 3/20 | 0.34 |
| ▸ | AKT2 | P31751 | 3/20 | 0.34 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200348 | 0.83 | NAAA (0.40) | NAAAEPHX1HTTCHRM2CHRM1 | |
| SCHEMBL18856334 | 0.80 | NAAA (0.41) | NAAAEPHX1HTTCHRM2CHRM1 | |
| SCHEMBL19669582 | 0.80 | AKT1 (0.38) | NAAAEPHX1HTTAKT1AKT2 | |
| SCHEMBL19669585 | 0.79 | EPHX1 (0.42) | NAAAEPHX1HTTAKT1AKT2 | |
| SCHEMBL6443081 | 0.78 | PRKCA (0.40) | NAAAEPHX1CHRM2CHRM1CHRM3 | |
| SCHEMBL15444724 | 0.78 | EPHX1 (0.41) | NAAAEPHX1HTTAKT1AKT2 | |
| SCHEMBL6272147 | 0.77 | NAAA (0.39) | NAAAEPHX1HTTSMN1; SMN2CYP19A1 | |
| SCHEMBL8220029 | 0.77 | EPHX1 (0.44) | NAAAEPHX1HTTSMN1; SMN2CYP19A1 | |
| SCHEMBL304317 | 0.76 | EPHX1 (0.44) | NAAAEPHX1HTTCYP19A1CYP2C19 | |
| SCHEMBL6448762 | 0.76 | CHRM2 (0.36) | NAAAEPHX1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |