Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 13/20 | 0.63 |
| ▸ | PTAFR | P25105 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201787 | 0.89 | NISCH (0.62) | NISCH | |
| SCHEMBL8189633 | 0.84 | NISCH (0.71) | NISCHALDH1A1 | |
| Hydrochloric Acid SCHEMBL8201249 | 0.83 | NISCH (0.44) | NISCHPTAFRALDH1A1PARP1MAOB | |
| SCHEMBL8204316 | 0.81 | NISCH (0.74) | NISCHMAOB | |
| SCHEMBL8202555 | 0.81 | NISCH (0.48) | NISCHPTAFRALDH1A1MAOBPARP10 | |
| SCHEMBL10822807 | 0.79 | MAPT (0.52) | NISCHALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7736305 | 0.79 | NISCH (0.48) | NISCHALDH1A1PARP1MAOB | |
| SCHEMBL8201474 | 0.78 | NISCH (0.69) | NISCHMAOB | |
| SCHEMBL17840165 | 0.78 | RORC (0.57) | ALDH1A1MAOB | |
| Hydrochloric Acid SCHEMBL7736307 | 0.78 | NISCH (0.42) | NISCHALDH1A1PARP1MAOBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |