Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19111144 | 0.78 | PIK3CA (0.33) | ESR1 | |
| SCHEMBL10223944 | 0.77 | ESR1 (0.45) | ESR1 | |
| SCHEMBL10103887 | 0.77 | CCR1 (0.44) | ESR1 | |
| SCHEMBL12162565 | 0.75 | GBA1 (0.46) | ESR1 | |
| SCHEMBL1515229 | 0.75 | BRS3 (0.40) | ESR1 | |
| SCHEMBL2611199 | 0.75 | RAB9A (0.37) | ESR1 | |
| SCHEMBL10245078 | 0.75 | TRPA1 (0.37) | — | |
| SCHEMBL21325077 | 0.74 | ESR1 (0.33) | ESR1 | |
| SCHEMBL15342096 | 0.73 | HRH3 (0.47) | ESR1 | |
| SCHEMBL13547890 | 0.73 | ESR1 (0.40) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033389-A2 | MACROCYCLIC HCV INHIBITORS AND THEIR USES | NOVARTIS AG (CH) | 2008-03-20 | — | — | WO | disclosed |