Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200614 | 0.79 | IKBKB (0.38) | L3MBTL1LMNAALDH1A1RAB9AUSP2 | |
| SCHEMBL8195677 | 0.77 | KMT2A (0.39) | L3MBTL1LMNARAB9ATSHRMAPK1 | |
| SCHEMBL8200611 | 0.72 | USP2 (0.33) | LMNAUSP2HSD17B10ACHE | |
| SCHEMBL8200604 | 0.71 | NAMPT (0.35) | LMNANAMPT | |
| SCHEMBL7983311 | 0.71 | HDAC3 (0.38) | L3MBTL1LMNAALDH1A1RAB9AHSD17B10 | |
| SCHEMBL7979087 | 0.71 | HDAC3 (0.38) | L3MBTL1LMNAALDH1A1RAB9AHSD17B10 | |
| SCHEMBL7980978 | 0.71 | HDAC3 (0.38) | L3MBTL1LMNAALDH1A1RAB9AHSD17B10 | |
| SCHEMBL7977138 | 0.71 | HDAC3 (0.38) | L3MBTL1LMNAALDH1A1RAB9AHSD17B10 | |
| SCHEMBL7980452 | 0.71 | HDAC3 (0.38) | L3MBTL1LMNAALDH1A1RAB9AHSD17B10 | |
| SCHEMBL10536719 | 0.67 | TAAR1 (0.61) | L3MBTL1LMNAALDH1A1HSD17B10TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |