Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198968 | 0.81 | IKBKB (0.44) | IKBKBNAMPTL3MBTL1MAPK1LMNA | |
| SCHEMBL8195688 | 0.80 | IKBKB (0.43) | IKBKBNAMPTL3MBTL1MAPK1LMNA | |
| SCHEMBL8200604 | 0.79 | NAMPT (0.35) | NAMPTLMNASMN1; SMN2 | |
| SCHEMBL8196335 | 0.79 | LMNA (0.38) | IKBKBNAMPTL3MBTL1MAPK1LMNA | |
| SCHEMBL8200611 | 0.79 | USP2 (0.33) | LMNASMN1; SMN2USP2HSD17B10 | |
| SCHEMBL8200607 | 0.79 | L3MBTL1 (0.36) | NAMPTL3MBTL1TSHRMAPK1TAAR1 | |
| SCHEMBL8195627 | 0.76 | IKBKB (0.46) | IKBKBNAMPTL3MBTL1TSHRLMNA | |
| SCHEMBL14324543 | 0.74 | KDM4E (0.44) | IKBKBL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL12336170 | 0.74 | KDM4E (0.44) | IKBKBL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL14324544 | 0.74 | KDM4E (0.44) | IKBKBL3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |