Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.33 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977997 | 0.81 | LATS1 (0.37) | NAMPTIMPDH2QPCTLMNAHRH4 | |
| SCHEMBL7978001 | 0.81 | LATS1 (0.37) | NAMPTIMPDH2QPCTLMNAHRH4 | |
| SCHEMBL8196331 | 0.79 | ADRB2 (0.36) | NAMPTIMPDH2ADRB2ADRB1ADRB3 | |
| SCHEMBL8196333 | 0.79 | ADRB2 (0.36) | NAMPTIMPDH2ADRB2ADRB1ADRB3 | |
| SCHEMBL8200614 | 0.79 | IKBKB (0.38) | NAMPTSMN1; SMN2LMNA | |
| SCHEMBL8919392 | 0.79 | HRH4 (0.48) | NAMPTSMN1; SMN2IMPDH2ADRB2ADRB1 | |
| SCHEMBL8195623 | 0.76 | MEN1 (0.44) | NAMPTSMN1; SMN2IMPDH2LMNAGAA | |
| SCHEMBL8195619 | 0.76 | MEN1 (0.44) | NAMPTSMN1; SMN2IMPDH2LMNAGAA | |
| SCHEMBL8915410 | 0.76 | HRH4 (0.45) | NAMPTIMPDH2ADRB2ADRB1ADRB3 | |
| SCHEMBL6950781 | 0.75 | CYP3A4 (0.46) | NAMPTIMPDH2ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |