⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21614042 | 0.82 | — | — | |
| SCHEMBL28902273 | 0.75 | DGAT1 (0.42) | — | |
| SCHEMBL29728523 | 0.75 | ALOX15 (0.36) | — | |
| SCHEMBL21482171 | 0.75 | ALOX15 (0.36) | — | |
| SCHEMBL3094 | 0.75 | — | — | |
| SCHEMBL28325001 | 0.75 | DGAT1 (0.42) | — | |
| SCHEMBL30234788 | 0.75 | DGAT1 (0.42) | — | |
| Methylamine SCHEMBL25305181 | 0.73 | DGAT1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL8549932 | 0.73 | DGAT1 (0.40) | — | |
| SCHEMBL17377683 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205206-A1 | LINCOSAMIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023146989-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023049218-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-30 | — | — | WO | disclosed |
| EP-4153747-A2 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | Wave Life Sciences Ltd. (SG) | 2023-03-29 | — | — | EP | disclosed |
| WO-2021234459-A9 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2022-02-03 | — | — | WO | disclosed |
| WO-2021234459-A2 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |
| WO-2021138537-A1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES WITH IMPROVED SYSTEMIC DELIVERY | PHIO PHARMACEUTICALS CORP. (US) | 2021-07-08 | — | — | WO | disclosed |
| EP-3709998-A1 | NOVEL IMIDAZOPYRIMIDINE COMPOUNDS AND USES THEREOF | Children's Medical Center Corporation (US) | 2020-09-23 | — | — | EP | disclosed |
| WO-2013184564-A1 | METHODS AND INTERMEDIATES FOR THE PREPARATION OF FONDAPARINUX | ACADEMIA SINICA (TW) | 2013-12-12 | — | — | WO | disclosed |
| WO-2012027555-A2 | GLYCATED CD59 PEPTIDES, THEIR PREPARATION, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-03-01 | — | — | WO | disclosed |
| EP-0970066-A1 | AMINOEPOXIDES FROM AMINOALDEHYDES AND IN-SITU FORMED HALOMETHYL ORGANOMETALLIC REAGENT | G.D. SEARLE & CO. (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998029401-A1 | AMINOEPOXIDES FROM AMINOALDEHYDES AND IN-SITU FORMED HALOMETHYL ORGANOMETALLIC REAGENT | G.D. SEARLE & CO. (US) | 1998-07-09 | — | — | WO | disclosed |