Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.50 |
| ▸ | RARB | P10826 | 10/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181773 | 1.00 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL8178707 | 0.91 | ALDH1A1 (0.45) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL8178705 | 0.91 | ALDH1A1 (0.45) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL3184382 | 0.84 | PTPN11 (0.55) | PTPN11ALDH1A1 | |
| SCHEMBL8181779 | 0.83 | PTPN11 (0.68) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL8170024 | 0.82 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL9651201 | 0.82 | PTPN11 (0.57) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL9149323 | 0.82 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL8170027 | 0.82 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL8200723 | 0.82 | PTPN11 (0.50) | PTPN11RARBMEN1ALDH1A1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143208-A | Optical element and compounds used in its manufacture | ROLIC AG (CH) | 2000-11-07 | — | — | US | disclosed |
| US-5335303-A | Quasi-phased matched optical waveguide frequency conversion element having a ferroelectric liquid crystalline material exhibiting a periodic structure | HOFFMANN-LA ROCHE INC. (US) | 1994-08-02 | — | — | US | disclosed |