Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857678 | 0.85 | MEN1 (0.63) | MEN1KMT2AGUSBFOLH1MRGPRX4 | |
| SCHEMBL6459667 | 0.83 | MEN1 (0.61) | MEN1KMT2ACYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL5747177 | 0.83 | MEN1 (0.61) | MEN1KMT2ACYP4F2CYP4A11NR1H2 | |
| SCHEMBL11459736 | 0.83 | ENPP2 (0.50) | KMT2AALDH1A1TSHRFOLH1MRGPRX4 | |
| SCHEMBL6453539 | 0.82 | KMT2A (0.59) | MEN1KMT2ANR1H2NR1H3ALDH1A1 | |
| SCHEMBL2849191 | 0.80 | CYP4F2 (0.68) | MEN1KMT2ACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL11580792 | 0.79 | MEN1 (0.44) | MEN1KMT2ANR1H2NR1H3ALDH1A1 | |
| SCHEMBL5207992 | 0.79 | CYP4F2 (0.45) | CYP4F2CYP4A11ALDH1A1TSHRFOLH1 | |
| SCHEMBL3892580 | 0.77 | KAT6A (0.50) | CYP4F2CYP4A11ALDH1A1TSHRFOLH1 | |
| SCHEMBL27447668 | 0.77 | CYP4F2 (0.44) | CYP4F2CYP4A11ALDH1A1TSHRFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447134-B2 | Compounds and methods for treating mammalian gastrointestinal microbial infections | BRANDEIS UNIVERSITY (US) | 2016-09-20 | — | — | US | disclosed |
| WO-2014028931-A2 | COMPOUNDS AND METHODS FOR TREATING MAMMALIAN GASTROINTESTINAL MICROBIAL INFECTIONS | BRANDEIS UNIVERSITY (US) | 2014-02-20 | — | — | WO | disclosed |
| CN-1253543-A | Process for producing ketoprofen and 5-benzoyl-3-methyl-2-indolinone | MEDICAL INFORMATION SERVICES I (JP) | 2000-05-17 | — | — | CN | disclosed |
| EP-0990637-A1 | PROCESS FOR PRODUCING KETOPROFEN AND 5-BENZOYL-3-METHYL-2-INDOLINONE | Medical Information Services, Inc. (JP) | 2000-04-05 | — | — | EP | disclosed |
| EP-0209905-B1 | 1,1-(3-ETHYLPHENYL)PHENYLETHYLENE AND METHOD FOR ITS PREPARATION | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1989-03-01 | — | — | EP | disclosed |
| US-4761508-A | 1,1-(3-ethylphenyl)phenylethylene and method for preparing it | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1988-08-02 | — | — | US | disclosed |
| EP-0209905-A1 | 1,1-(3-Ethylphenyl)phenylethylene and method for its preparation | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1987-01-28 | — | — | EP | disclosed |