Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 2/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857678 | 0.87 | MEN1 (0.63) | KMT2AMEN1GUSB | |
| SCHEMBL11277259 | 0.85 | L3MBTL1 (0.55) | ATMTDP1L3MBTL1SRD5A2PBRM1 | |
| SCHEMBL6158425 | 0.83 | L3MBTL1 (0.57) | KMT2AMEN1ATMTDP1L3MBTL1 | |
| SCHEMBL8200768 | 0.82 | MEN1 (0.61) | KMT2AMEN1ALDH1A1NR1H2NR1H3 | |
| SCHEMBL5747177 | 0.82 | MEN1 (0.61) | KMT2AMEN1NR1H2NR1H3 | |
| SCHEMBL6459667 | 0.82 | MEN1 (0.61) | KMT2AMEN1 | |
| SCHEMBL27676657 | 0.81 | CYP4F2 (0.60) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7394259 | 0.80 | TDP1 (0.61) | ATMTDP1L3MBTL1SRD5A2PBRM1 | |
| SCHEMBL4669025 | 0.80 | TDP1 (0.61) | ATMTDP1L3MBTL1SRD5A2PBRM1 | |
| SCHEMBL2849191 | 0.78 | CYP4F2 (0.68) | KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606248-A2 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompé S.P.A. (IT) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004080951-A2 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE S.P.A. (IT) | 2004-09-23 | — | — | WO | disclosed |
| US-4230884-A | METHYLATION, HYDROLYSIS, WITH CATALYST | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV, N.SOL.O. (YU) | 1980-10-28 | — | — | US | disclosed |