Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381989 | 1.00 | SLC10A2 (0.85) | SLC10A2 | |
| Hydrochloric Acid SCHEMBL8378774 | 0.99 | SLC10A2 (0.83) | SLC10A2 | |
| Hydrochloric Acid SCHEMBL8383749 | 0.99 | SLC10A2 (0.83) | SLC10A2 | |
| SCHEMBL9961463 | 0.92 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL349300 | 0.92 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL1993533 | 0.92 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL349299 | 0.92 | SLC10A2 (1.00) | SLC10A2 | |
| Hydrochloric Acid SCHEMBL8378730 | 0.91 | SLC10A2 (0.98) | SLC10A2 | |
| SCHEMBL7479825 | 0.90 | SLC10A2 (0.83) | SLC10A2 | |
| SCHEMBL7473952 | 0.90 | SLC10A2 (0.83) | SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971744-A2 | COMBINATION THERAPY EMPLOYING ILEAL BILE ACID TRANSPORT INHIBITING BENZOTHIEPINES AND HMG Co-A REDUCTASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-01-19 | — | — | EP | disclosed |
| EP-0626952-B1 | HYPOLIPIDAEMIC BENZOTHIAZEPINE COMPOUNDS | WELLCOME FOUND (GB) | 1999-04-14 | — | — | EP | disclosed |
| US-5859240-A | REDUCTION OF IMINE GROUP; OXIDATION; SALT FORMATION | GLAXO WELLCOME INC. (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1998040375-A2 | COMBINATION OF ILEAL BILE ACID TRANSPORT INHIBITING BENZOTHIEPINES AND HMG Co-A REDUCTASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-09-17 | — | — | WO | disclosed |
| US-5663165-A | ANTICHOLESTEROL, CARDIOVASCULAR | GLAXO WELLCOME INC. (US) | 1997-09-02 | — | — | US | disclosed |