⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089767 | 1.00 | — | — | |
| SCHEMBL8089770 | 1.00 | — | — | |
| SCHEMBL8083215 | 0.80 | KCNH2 (0.32) | — | |
| SCHEMBL8097423 | 0.78 | KDM1A (0.31) | — | |
| SCHEMBL8083212 | 0.74 | NOS3 (0.30) | — | |
| SCHEMBL7851192 | 0.71 | NFKB1 (0.39) | — | |
| SCHEMBL8693432 | 0.71 | NFKB1 (0.39) | — | |
| SCHEMBL7851194 | 0.71 | NFKB1 (0.39) | — | |
| SCHEMBL7851189 | 0.71 | NFKB1 (0.39) | — | |
| SCHEMBL8094739 | 0.71 | NFKB1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682030-B1 | 8-Amino-10(azabicycloalkyl)-pyrido[1,2,3-d,e] [1,3,4] benzoxadiazine derivatives, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 2000-07-05 | — | — | EP | disclosed |
| EP-0647644-B1 | Antibacterial pyrido 1,2,3-d,e 1,3,4 benzoxacin derivatives | BAYER AG (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0588166-B1 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| US-5508278-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |
| EP-0682030-A1 | 8-Amino-10(azabicycloalkyl)-pyrido[1,2,3-d,e] [1,3,4] benzoxadiazine derivatives, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| EP-0647644-A1 | Antibacterial pyrido 1,2,3-d,e 1,3,4 benzoxacin derivatives | BAYER AG (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0588166-A2 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |