Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | HPGD | P15428 | 4/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.77 |
| ▸ | GAA | P10253 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18177337 | 0.87 | MAPT (1.00) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL5322468 | 0.81 | MAPT (0.73) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL689546 | 0.78 | ALDH1A1 (1.00) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL1799330 | 0.77 | KMT2A (0.69) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL8196570 | 0.75 | ALDH1A1 (0.62) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL8188234 | 0.75 | KMT2A (0.65) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL27749754 | 0.73 | HSD17B10 (0.63) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL13838083 | 0.72 | PRKCZ (0.61) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL12465762 | 0.72 | PRKCZ (0.47) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL28760465 | 0.72 | ALDH1A1 (0.54) | MAPTALDH1A1HPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063668-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |