SCHEMBL8201097

SCHEMBL8201097

CC(C)(C)OC(=O)C(N)CCNC(=O)c1ccc2c(c1)C(=O)c1ccccc1C2=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 4/20 0.61
TERT O14746 6/20 0.53
GRIN1 Q05586 1/20 0.52
GRIN2A Q12879 1/20 0.52
GRIN2B Q13224 1/20 0.52
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
ATM Q13315 1/20 0.50
CTSL P07711 1/20 0.47
PTPN13 Q12923 1/20 0.47
MAPK14 Q16539 2/20 0.46
ALDH1A1 P00352 3/20 0.45
KMT2A Q03164 2/20 0.45
HPGD P15428 2/20 0.45
MEN1 O00255 1/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
PKM P14618 1/20 0.45
HSD17B10 Q99714 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2601917 0.82 PTPRC (0.68) PTPRCTERTGRIN1GRIN2AGRIN2B
SCHEMBL8201092 0.81 PTPRC (0.65) PTPRCTERTGRIN1GRIN2AGRIN2B
SCHEMBL20978557 0.78 PTPRC (0.61) PTPRCTERTGRIN1GRIN2AGRIN2B
SCHEMBL6261925 0.76 PTPRC (1.00) PTPRCTERTGRIN1GRIN2AGRIN2B
SCHEMBL18015978 0.76 TERT (0.59) PTPRCTERTGRIN1GRIN2AGRIN2B
SCHEMBL8197262 0.75 PTPRC (0.71) PTPRCTERTGRIN1GRIN2AGRIN2B
SCHEMBL21131326 0.74 TERT (0.68) PTPRCTERTGRIN1GRIN2AGRIN2B
SCHEMBL15085172 0.74 TERT (0.64) PTPRCTERTGRIN1GRIN2AGRIN2B
SCHEMBL6260964 0.74 PTPRC (1.00) PTPRCTERTGRIN1GRIN2AGRIN2B
SCHEMBL27728858 0.74 PTPRC (0.62) PTPRCNPC1RAB9AATMCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0820483-B1 METHOD OF PHOTOCHEMICAL IMMOBILIZATION OF LIGANDS USING QUINONES JAKOBSEN MOGENS HAVSTEEN (DK) 2000-12-13 EP disclosed
US-6033784-A Method of photochemical immobilization of ligands using quinones JAKOBSEN MOGENS HAVSTEEN (DK) 2000-03-07 US disclosed