SCHEMBL820118

SCHEMBL820118

COCC(C(=O)Cl)C1C2CC3CC(C2)CC1C3

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.36
HSD11B1 P28845 1/20 0.33
MAPK1 P28482 1/20 0.33
EPHX2 P34913 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888272 0.84 EPHX1 (0.38) EPHX1HSD11B1MAPK1EPHX2L3MBTL1
SCHEMBL819516 0.83 L3MBTL1 (0.33) EPHX1HSD11B1EPHX2L3MBTL1
SCHEMBL888546 0.81 MAPK1 (0.41) EPHX1HSD11B1MAPK1EPHX2L3MBTL1
SCHEMBL819751 0.81 HSD11B1 (0.33) EPHX1HSD11B1EPHX2
SCHEMBL820370 0.70 NPSR1 (0.38) EPHX1EPHX2MEN1KMT2AALDH1A1
SCHEMBL888449 0.70 L3MBTL1 (0.35) EPHX1HSD11B1MAPK1EPHX2L3MBTL1
SCHEMBL819198 0.69 NPSR1 (0.41) EPHX1EPHX2MEN1KMT2AALDH1A1
SCHEMBL6555589 0.69 HSD11B1 (0.39) EPHX1HSD11B1EPHX2L3MBTL1ALDH1A1
SCHEMBL6555586 0.69 HSD11B1 (0.39) EPHX1HSD11B1EPHX2L3MBTL1ALDH1A1
SCHEMBL4138803 0.69 EPHX2 (0.46) EPHX1HSD11B1EPHX2L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288488-B2 Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-16 US disclosed
US-20110269929-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed