Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190619 | 0.84 | KCNH2 (0.53) | KCNH2DNMT1EHMT2HRH1ALDH1A1 | |
| SCHEMBL7472985 | 0.84 | LMNA (0.56) | KCNH2DNMT1EHMT2HRH1ALDH1A1 | |
| SCHEMBL7477007 | 0.83 | KCNH2 (0.62) | KCNH2HRH1ALDH1A1 | |
| SCHEMBL3824647 | 0.83 | BCHE (0.51) | KCNH2DNMT1EHMT2HRH1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7473216 | 0.82 | KCNH2 (0.60) | KCNH2HRH1 | |
| SCHEMBL8792369 | 0.82 | TSHR (0.55) | KCNH2DNMT1EHMT2HRH1ALDH1A1 | |
| SCHEMBL8948483 | 0.82 | KCNH2 (0.51) | KCNH2DNMT1EHMT2HRH1ALDH1A1 | |
| SCHEMBL8791275 | 0.82 | KCNH2 (0.60) | KCNH2DNMT1EHMT2HRH1ALDH1A1 | |
| SCHEMBL8792733 | 0.81 | KCNH2 (0.50) | KCNH2DNMT1EHMT2HRH1ALDH1A1 | |
| SCHEMBL8948348 | 0.81 | HRH1 (0.52) | FAAHKCNH2DNMT1EHMT2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017931-A | Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines | FMC CORPORATION | 2000-01-25 | — | — | US | disclosed |
| US-5639763-A | FOR AGRICULTURAL APPLICATIONS | FMC CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| US-5569664-A | AGRICULTURAL INSECTICIDES | FMC CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |