Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | UBE2I | P63279 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429397 | 0.85 | F2 (0.54) | DAOALDH1A1F2MAPTKMT2A | |
| SCHEMBL279675 | 0.85 | — | — | |
| SCHEMBL40949 | 0.81 | — | — | |
| Acetic Acid SCHEMBL28207221 | 0.80 | MAPT (0.47) | DAOALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL8946118 | 0.79 | MAPT (0.50) | DAOALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL28521661 | 0.79 | PARP10 (0.45) | ALDH1A1HPGDKDM4ELMNAUBE2I | |
| Trifluoroacetic Acid SCHEMBL5659511 | 0.74 | DAO (0.55) | DAOALDH1A1HPGDF2NPC1 | |
| SCHEMBL7799593 | 0.74 | PTGS1 (0.50) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL4155363 | 0.70 | F2 (0.46) | DAOALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL10674835 | 0.70 | DPP4 (0.53) | ALDH1A1HPGDKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973498-A1 | GASTROINTESTINAL MUCOSA-ADHERENT PHARMACEUTICAL COMPOSITION | Takeda Chemical Industries, Ltd. (JP) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998042311-A1 | GASTROINTESTINAL MUCOSA-ADHERENT PHARMACEUTICAL COMPOSITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |