Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 5/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201286 | 0.91 | MAPT (0.49) | SLC6A9SLC6A5MAPTTDP1KMT2A | |
| SCHEMBL8201996 | 0.85 | SLC6A9 (0.48) | SLC6A9SLC6A5MAPTTDP1KMT2A | |
| SCHEMBL8202557 | 0.83 | SLC6A9 (0.48) | SLC6A9SLC6A5MAPTTDP1KMT2A | |
| SCHEMBL8202238 | 0.81 | SLC6A9 (0.44) | SLC6A9SLC6A5MAPTTDP1KMT2A | |
| SCHEMBL8206298 | 0.81 | ADRB3 (0.46) | SLC6A9SLC6A5MAPTTDP1KMT2A | |
| SCHEMBL8719747 | 0.78 | TDP1 (0.49) | SLC6A9SLC6A5MAPTTDP1KMT2A | |
| SCHEMBL8201827 | 0.77 | ALDH1A1 (0.46) | SLC6A9SLC6A5MAPTTDP1KMT2A | |
| SCHEMBL8716300 | 0.76 | MAPT (0.45) | SLC6A9SLC6A5MAPTTDP1KMT2A | |
| SCHEMBL8204140 | 0.75 | ALDH1A1 (0.44) | SLC6A9SLC6A5MAPTTDP1KMT2A | |
| SCHEMBL8201916 | 0.74 | KMT2A (0.52) | MAPTTDP1KMT2AMEN1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013673-A | ADMINISTERING AN EFFECTIVE AMOUNT OF A NAPHTHYLOXYACETIC ACID DERIVATIVE OR NONTOXIC ACID ADDITION SALT OR HYDRATE TO TREAT OR PREVENT ABORTION, PAINE, DIARRHEA, CATHARTICS, ULCER, GASTRITIS, HYPERTENSION AND THROMBOSIS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-01-11 | — | — | US | claimed |
| EP-0719760-A1 | Naphthyloxyacetic acid derivatives and their use as PGW2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | claimed |
| US-6013673-A | ADMINISTERING AN EFFECTIVE AMOUNT OF A NAPHTHYLOXYACETIC ACID DERIVATIVE OR NONTOXIC ACID ADDITION SALT OR HYDRATE TO TREAT OR PREVENT ABORTION, PAINE, DIARRHEA, CATHARTICS, ULCER, GASTRITIS, HYPERTENSION AND THROMBOSIS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-01-11 | — | — | US | disclosed |
| EP-0719760-B1 | Naphthalene derivatives and their use as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1999-09-22 | — | — | EP | disclosed |
| EP-0719760-A1 | Naphthyloxyacetic acid derivatives and their use as PGW2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |