Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 1.00 |
| ▸ | HTR1B | P28222 | 7/20 | 0.78 |
| ▸ | HTR1A | P08908 | 2/20 | 0.78 |
| ▸ | HTR1D | P28221 | 5/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201469 | 1.00 | HTR6 (1.00) | HTR6HTR1BHTR1AHTR1D | |
| SCHEMBL8790464 | 0.87 | HTR1B (1.00) | HTR6HTR1BHTR1AHTR1D | |
| SCHEMBL5819877 | 0.87 | HTR1B (1.00) | HTR6HTR1BHTR1AHTR1D | |
| SCHEMBL5819875 | 0.87 | HTR1B (1.00) | HTR6HTR1BHTR1AHTR1D | |
| SCHEMBL8790505 | 0.86 | HTR1B (0.93) | HTR6HTR1BHTR1AHTR1D | |
| SCHEMBL8790496 | 0.86 | HTR1B (0.93) | HTR6HTR1BHTR1AHTR1D | |
| SCHEMBL8932357 | 0.83 | HTR1B (0.76) | HTR6HTR1BHTR1AHTR1D | |
| SCHEMBL8932358 | 0.83 | HTR1B (0.76) | HTR6HTR1BHTR1AHTR1D | |
| SCHEMBL1122175 | 0.82 | HTR1B (0.76) | HTR6HTR1BHTR1AHTR1D | |
| SCHEMBL1122542 | 0.82 | HTR1B (0.76) | HTR6HTR1BHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100291-A | FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-08-08 | — | — | US | disclosed |