SCHEMBL820150

SCHEMBL820150

C=C(CCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)NC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819528 0.87
SCHEMBL819801 0.87
SCHEMBL28413932 0.80
SCHEMBL28461761 0.78
SCHEMBL403239 0.77 TBXAS1 (0.34)
SCHEMBL5908106 0.76
SCHEMBL3761055 0.75
SCHEMBL8645372 0.74
SCHEMBL373899 0.73 FNTA (0.33)
SCHEMBL373896 0.73 FNTA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924612-A Corneal contact lens and silicone contact lens 望隼科技股份有限公司 2024-04-26 CN claimed
CN-113480736-A Hydrophilized polydiorganosiloxane vinyl crosslinkers and uses thereof 爱尔康公司 2021-10-08 CN claimed
CN-113166340-A Hydrogel composition 眼科公司 2021-07-23 CN claimed
US-7584630-B2 Photochromic ocular devices TRANSITIONS OPTICAL, INC. (US) 2009-09-08 US claimed
EP-1604231-B9 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC (US) 2009-01-07 EP claimed
EP-1604231-B1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC (US) 2008-07-02 EP claimed
JP-2007524857-A 2007-08-30 JP claimed
US-20070113587-A1 Photochromic ocular devices TRANSITIONS OPTICAL LIMITED (IE) 2007-05-24 US claimed
EP-1604231-A1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL, INC. (US) 2005-12-14 EP claimed
WO-2004086103-A1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC. (US) 2004-10-07 WO claimed
US-20040186241-A1 Photochromic ocular devices TRANSITIONS OPTICAL, INC. 2004-09-23 US claimed
EP-0396364-B1 Copolymers of vinyl carbonate and vinyl carbamate as contact lens material BAUSCH & LOMB (US) 1997-06-11 EP claimed
CN-117924612-A Corneal contact lens and silicone contact lens 望隼科技股份有限公司 2024-04-26 CN disclosed
CN-114502362-B Contact lenses with surfaces of different softness 爱尔康公司 2024-03-26 CN disclosed
CN-115605529-B Photochromic polydiorganosiloxane vinyl cross-linking agent 爱尔康公司 2024-03-26 CN disclosed
CN-116867836-A Hydrophilized polydiorganosiloxane vinyl cross-linking agent 爱尔康公司 2023-10-10 CN disclosed
US-20110282008-A1 SILICONE MONOMER NOF CORPORATION (JP) 2011-11-17 US disclosed
US-20080002146-A1 BIOCOMPATIBLE, SURFACE MODIFIED MATERIALS BAUSCH & LOMB INCORPORATED 2008-01-03 US disclosed
US-20060012750-A1 Monomer composition and polysmers and ophthalmic lenses in which it is used JOHNSON & JOHNSON VISION CARE, INC. 2006-01-19 US disclosed
CN-1299387-A Plasma surface treatment of silicone hydrogel contact lenses BAUSCH & LUMB INC (US) 2001-06-13 CN disclosed