Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PREP | P48147 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201531 | 1.00 | GFER (0.58) | GFERMEN1KMT2APREPNPSR1 | |
| SCHEMBL8508418 | 1.00 | GFER (0.58) | GFERMEN1KMT2APREPNPSR1 | |
| SCHEMBL30053426 | 0.90 | NPSR1 (0.51) | GFERPREPNPSR1ALDH1A1TP53 | |
| SCHEMBL29206541 | 0.90 | NPSR1 (0.51) | GFERPREPNPSR1ALDH1A1TP53 | |
| SCHEMBL30877842 | 0.90 | NPSR1 (0.51) | GFERPREPNPSR1ALDH1A1TP53 | |
| SCHEMBL8208547 | 0.90 | NPSR1 (0.51) | GFERPREPNPSR1ALDH1A1TP53 | |
| SCHEMBL8208549 | 0.90 | NPSR1 (0.51) | GFERPREPNPSR1ALDH1A1TP53 | |
| SCHEMBL30053580 | 0.90 | NPSR1 (0.51) | GFERPREPNPSR1ALDH1A1TP53 | |
| SCHEMBL30055 | 0.89 | GABRA1 (0.56) | KMT2APREPNPSR1TSHRL3MBTL1 | |
| SCHEMBL30056 | 0.89 | GABRA1 (0.56) | KMT2APREPNPSR1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100291-A | FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-08-08 | — | — | US | disclosed |
| US-5998462-A | SEROTONIN RECEPTOR ANTAGONIST | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1999-12-07 | — | — | US | disclosed |