Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PREP | P48147 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208547 | 1.00 | NPSR1 (0.51) | NPSR1PREPTSHRL3MBTL1KLK7 | |
| SCHEMBL29206541 | 1.00 | NPSR1 (0.51) | NPSR1PREPTSHRL3MBTL1KLK7 | |
| SCHEMBL30053580 | 1.00 | NPSR1 (0.51) | NPSR1PREPTSHRL3MBTL1KLK7 | |
| SCHEMBL30877842 | 1.00 | NPSR1 (0.51) | NPSR1PREPTSHRL3MBTL1KLK7 | |
| SCHEMBL30053426 | 1.00 | NPSR1 (0.51) | NPSR1PREPTSHRL3MBTL1KLK7 | |
| SCHEMBL30053286 | 0.91 | PREP (0.48) | NPSR1PREPTSHRL3MBTL1KLK7 | |
| SCHEMBL30056 | 0.90 | GABRA1 (0.56) | NPSR1PREPTSHRL3MBTL1KLK7 | |
| SCHEMBL8209315 | 0.90 | GABRA1 (0.56) | NPSR1PREPTSHRL3MBTL1KLK7 | |
| SCHEMBL30055 | 0.90 | GABRA1 (0.56) | NPSR1PREPTSHRL3MBTL1KLK7 | |
| SCHEMBL8201527 | 0.90 | GFER (0.58) | NPSR1PREPTSHRL3MBTL1KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100291-A | FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-08-08 | — | — | US | disclosed |