Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208038 | 1.00 | HTR6 (1.00) | HTR6 | |
| SCHEMBL8208531 | 0.90 | HTR6 (1.00) | HTR6 | |
| SCHEMBL8208527 | 0.90 | HTR6 (1.00) | HTR6 | |
| SCHEMBL8201522 | 0.88 | HTR6 (0.84) | HTR6 | |
| SCHEMBL8201520 | 0.88 | HTR6 (0.84) | HTR6 | |
| SCHEMBL8201580 | 0.87 | HTR6 (0.79) | HTR6 | |
| SCHEMBL8201578 | 0.87 | HTR6 (0.79) | HTR6 | |
| SCHEMBL8208097 | 0.84 | HTR6 (0.73) | HTR6 | |
| SCHEMBL8201599 | 0.82 | HTR6 (0.76) | HTR6 | |
| SCHEMBL8201604 | 0.82 | HTR6 (0.76) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100291-A | FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-08-08 | — | — | US | claimed |
| WO-1999047516-A1 | 3-(2-PYRROLIDINYLMETHYL)-INDOLE COMPOUNDS HAVING 5-HT6 AFFINITY | SLASSI ABDELMALIK (CA) | 1999-09-23 | — | — | WO | claimed |
| US-6100291-A | FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-08-08 | — | — | US | disclosed |
| EP-0932420-A4 | DRUG DELIVERY USING TERMINAL COMPLEMENT COMPONENTS | HARVARD COLLEGE (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999047516-A1 | 3-(2-PYRROLIDINYLMETHYL)-INDOLE COMPOUNDS HAVING 5-HT6 AFFINITY | SLASSI ABDELMALIK (CA) | 1999-09-23 | — | — | WO | disclosed |
| EP-0932420-A1 | DRUG DELIVERY USING TERMINAL COMPLEMENT COMPONENTS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1997040857-A1 | DRUG DELIVERY USING TERMINAL COMPLEMENT COMPONENTS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1997-11-06 | — | — | WO | disclosed |