Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2370159 | 1.00 | KMT2A (0.46) | KMT2AHTR2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL2696782 | 1.00 | KMT2A (0.46) | KMT2AHTR2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5061699 | 1.00 | KMT2A (0.46) | KMT2AHTR2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL20384849 | 0.94 | KMT2A (0.42) | KMT2AHTR2AGRIN2DGRIN3BGRIN1 | |
| Benzonitrile SCHEMBL8546884 | 0.84 | TSHR (0.47) | KMT2AHTR2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL31546141 | 0.78 | KMT2A (0.39) | KMT2A | |
| SCHEMBL7108519 | 0.77 | IDO1 (0.47) | HTR2A | |
| SCHEMBL28971366 | 0.77 | IDO1 (0.47) | HTR2A | |
| SCHEMBL5852603 | 0.77 | IDO1 (0.47) | HTR2A | |
| SCHEMBL1109727 | 0.77 | IDO1 (0.47) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286160-A1 | SUBSTITUTED PIPERAZINES AS CB1 ANTAGONISTS | INTERVET INC. | 2010-11-11 | — | — | US | disclosed |
| US-20080119510-A1 | Substituted Imidazo [4,5-B] Pyridines As Inhibitors Of Gastric Acid Secretion | ALTANA PHARMA AG (DE) | 2008-05-22 | — | — | US | disclosed |
| CN-1279714-A | Epoxide hydrolase | PURATOS NV (BE) | 2001-01-10 | — | — | CN | disclosed |
| EP-1025213-A1 | EPOXIDE HYDROLASE | PURATOS N.V. (BE) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999021972-A1 | EPOXIDE HYDROLASE | PURATOS NAAMLOZE VENNOOTSCHAP (BE) | 1999-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286160-A1 | SUBSTITUTED PIPERAZINES AS CB1 ANTAGONISTS | CNR1, CNR2, GPR119 | KMT2A 1954/4885HTR2A 37/4885GRIN2D 356/4885 |
| US-20080119510-A1 | Substituted Imidazo [4,5-B] Pyridines As Inhibitors Of Gastric Acid Secretion | GIPR, CCKBR, GRPR | KMT2A 3874/4885HTR2A 1970/4885GRIN2D 3108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.