Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
| ▸ | HEXB | P07686 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethoxymethane SCHEMBL1228127 | 0.81 | CASP1 (0.39) | LMNASMN1; SMN2CASP1CCNA2CDK2 | |
| Ether SCHEMBL917077 | 0.81 | LMNA (0.41) | LMNASMN1; SMN2CASP1HSP90AA1ALDH1A1 | |
| Methoxymethane SCHEMBL108410 | 0.79 | LMNA (0.43) | LMNASMN1; SMN2CASP1CCNA2CDK2 | |
| SCHEMBL736034 | 0.79 | LMNA (0.40) | LMNASMN1; SMN2CASP1CCNA2CDK2 | |
| SCHEMBL10908182 | 0.79 | LMNA (0.40) | LMNASMN1; SMN2CASP1CCNA2CDK2 | |
| SCHEMBL28959694 | 0.77 | LMNA (0.38) | LMNASMN1; SMN2CASP1HSP90AA1ALDH1A1 | |
| SCHEMBL8214121 | 0.76 | TLR8 (0.42) | LMNASMN1; SMN2CASP1CCNA2CDK2 | |
| Ethylamine SCHEMBL23925800 | 0.76 | CASP1 (0.45) | LMNASMN1; SMN2CASP1CDK2CDK1 | |
| Butane SCHEMBL23581974 | 0.76 | CASP1 (0.45) | LMNASMN1; SMN2CASP1HSP90AA1HSD17B10 | |
| Ether SCHEMBL9622039 | 0.75 | LMNA (0.37) | LMNASMN1; SMN2CASP1HSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048610-A | MALEIC ANHYDRIDE FUNCTIONALIZED CHLORINATED POLYOLEFIN, A MALEIC ANHYDRIDE FUNCTIONALIZED BLOCK POLYSTYRENE COPOLYMER, AND A CROSSLINKING AGENT. | INTERTAPE POLYMER GROUP, INC. (US) | 2000-04-11 | — | — | US | disclosed |
| US-4199646-A | Heat-activatable, pressure-sensitive adhesive tape or sheet | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1980-04-22 | — | — | US | disclosed |