Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205485 | 0.77 | SLC6A3 (0.43) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL13595971 | 0.73 | SLC6A2 (0.81) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL14911800 | 0.70 | CYP3A4 (0.47) | — | |
| SCHEMBL1177861 | 0.69 | SLC6A2 (0.55) | SLC6A4SLC6A3SLC6A2CHRNA7 | |
| SCHEMBL1177859 | 0.69 | SLC6A2 (0.55) | SLC6A4SLC6A3SLC6A2CHRNA7 | |
| SCHEMBL9366067 | 0.69 | SLC6A2 (0.55) | SLC6A4SLC6A3SLC6A2CHRNA7 | |
| SCHEMBL4437035 | 0.68 | HRH3 (0.53) | — | |
| SCHEMBL6798152 | 0.68 | SLC6A2 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8419814 | 0.68 | SLC6A2 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8416666 | 0.68 | SLC6A2 (1.00) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060473-A | 7-azabicyclo[2.2.1]-heptane and -heptene derivatives as cholinergic receptor ligands | UCB S.A. - DTB (BE) | 2000-05-09 | — | — | US | disclosed |
| EP-0778835-A4 | 7-AZABICYCLO 2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS CHOLINERGIC RECEPTOR LIGANDS | UNIV VIRGINIA (US) | 1999-02-03 | — | — | EP | disclosed |
| EP-0778835-A1 | 7-AZABICYCLO 2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS CHOLINERGIC RECEPTOR LIGANDS | UNIVERSITY OF VIRGINIA (US) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996006093-A1 | 7-AZABICYCLO[2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS CHOLINERGIC RECEPTOR LIGANDS | UNIVERSITY OF VIRGINIA (US) | 1996-02-29 | — | — | WO | disclosed |