Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219961 | 0.77 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL8201858 | 0.77 | SLC6A4 (0.51) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL16278692 | 0.72 | TRPM5 (0.54) | SLC6A3SLC6A4OPRK1TRPM5SLC6A2 | |
| SCHEMBL16283864 | 0.72 | TRPM5 (0.54) | SLC6A3SLC6A4OPRK1TRPM5SLC6A2 | |
| SCHEMBL16278689 | 0.72 | TRPM5 (0.54) | SLC6A3SLC6A4OPRK1TRPM5SLC6A2 | |
| SCHEMBL7955583 | 0.71 | CHRNB2 (0.44) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7957728 | 0.71 | IDO1 (0.38) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7959490 | 0.71 | SLC6A3 (0.39) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7948346 | 0.69 | CHRNB2 (0.62) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7962213 | 0.68 | SLC6A4 (0.44) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060473-A | 7-azabicyclo[2.2.1]-heptane and -heptene derivatives as cholinergic receptor ligands | UCB S.A. - DTB (BE) | 2000-05-09 | — | — | US | disclosed |