Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 17/20 | 0.73 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202575 | 0.92 | CACNA1H (0.76) | CACNA1HMEN1ALDH1A1RECQLKMT2A | |
| SCHEMBL8209885 | 0.90 | CACNA1H (0.84) | CACNA1HALDH1A1 | |
| SCHEMBL12876303 | 0.87 | CACNA1H (0.70) | CACNA1HALDH1A1 | |
| SCHEMBL8212189 | 0.85 | CACNA1H (1.00) | CACNA1H | |
| SCHEMBL8201883 | 0.82 | CACNA1H (0.81) | CACNA1H | |
| SCHEMBL13596404 | 0.77 | CACNA1H (0.74) | CACNA1HMEN1ALDH1A1RECQLKMT2A | |
| SCHEMBL8202765 | 0.76 | TRPV1 (0.46) | CACNA1HTRPV1 | |
| SCHEMBL8202686 | 0.75 | CACNA1H (0.82) | CACNA1HTRPV1 | |
| SCHEMBL13595960 | 0.74 | CACNA1H (0.75) | CACNA1HMEN1ALDH1A1RECQLKMT2A | |
| SCHEMBL8202554 | 0.73 | CACNA1H (0.85) | CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033464-A2 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF DISORDERS OF THE LIPID METABOLISM | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |