Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202012 | 0.89 | CACNA1H (0.51) | TRPV1CACNA1H | |
| SCHEMBL8212825 | 0.89 | CACNA1H (0.55) | CACNA1HSMN1; SMN2 | |
| SCHEMBL12876238 | 0.87 | CACNA1H (0.58) | CACNA1HSMN1; SMN2 | |
| SCHEMBL8202719 | 0.84 | CACNA1H (0.63) | TRPV1CACNA1H | |
| SCHEMBL14263480 | 0.78 | CACNA1H (0.61) | TRPV1CACNA1H | |
| SCHEMBL14263481 | 0.77 | CACNA1H (0.63) | TRPV1CACNA1HMAPT | |
| SCHEMBL8201888 | 0.76 | CACNA1H (0.73) | TRPV1CACNA1H | |
| SCHEMBL14263435 | 0.76 | CACNA1H (0.69) | TRPV1CACNA1H | |
| SCHEMBL13596404 | 0.73 | CACNA1H (0.74) | CACNA1HLMNA | |
| SCHEMBL8210253 | 0.73 | CACNA1H (0.51) | TRPV1CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033464-A2 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF DISORDERS OF THE LIPID METABOLISM | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |