Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 15/20 | 0.82 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212189 | 0.90 | CACNA1H (1.00) | CACNA1H | |
| SCHEMBL8210812 | 0.83 | CACNA1H (0.71) | CACNA1HTRPV1 | |
| SCHEMBL8209885 | 0.82 | CACNA1H (0.84) | CACNA1HNPC1 | |
| SCHEMBL8202682 | 0.80 | CACNA1H (0.69) | CACNA1HTRPV1 | |
| SCHEMBL8210886 | 0.78 | CACNA1H (1.00) | CACNA1H | |
| SCHEMBL8202575 | 0.77 | CACNA1H (0.76) | CACNA1HMAPT | |
| SCHEMBL8202719 | 0.76 | CACNA1H (0.63) | CACNA1HTRPV1 | |
| SCHEMBL8201888 | 0.75 | CACNA1H (0.73) | CACNA1HTRPV1 | |
| SCHEMBL8202488 | 0.75 | CACNA1H (0.75) | CACNA1HTRPV1 | |
| SCHEMBL8210895 | 0.74 | CACNA1H (0.68) | CACNA1HTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033464-A2 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF DISORDERS OF THE LIPID METABOLISM | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |