Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8203133 | 0.82 | EPHX1 (0.37) | SSTR4EPHX1MEN1KMT2A | |
| SCHEMBL8210248 | 0.77 | EPHX1 (0.41) | CPN1CPB2ITGB3EPHX1CYP2D6 | |
| SCHEMBL27733842 | 0.72 | SMN1; SMN2 (0.41) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL21468160 | 0.72 | SMN1; SMN2 (0.41) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL8991906 | 0.72 | ALDH1A1 (0.42) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL1410684 | 0.72 | SMN1; SMN2 (0.41) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL3774861 | 0.71 | CYP2D6 (0.53) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL30063639 | 0.70 | SMN1; SMN2 (0.38) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL1410772 | 0.68 | ALDH1A1 (0.44) | ITGB3ITGB1ITGAVITGA5EPHX1 | |
| SCHEMBL30063536 | 0.67 | EPHX1 (0.43) | ITGB3ITGB1ITGAVITGA5EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053131-A1 | HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | CHROMA THERAPEUTICS LTD. (GB) | 2008-05-08 | — | — | WO | disclosed |