Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.41 |
| ▸ | CPN1 | P15169 | 3/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.36 |
| ▸ | F2R | P25116 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.35 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202611 | 0.81 | TPSAB1 (0.40) | EPHX1ALOX15TSHRANPEPERAP2 | |
| SCHEMBL3774861 | 0.81 | CYP2D6 (0.53) | EPHX1ITGB3CYP2D6 | |
| SCHEMBL8201908 | 0.77 | CPN1 (0.35) | EPHX1CPN1CPB2ALOX15ITGB3 | |
| Hydrochloric Acid SCHEMBL3458692 | 0.77 | EPHX1 (0.50) | EPHX1CPN1CPB2ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL19712555 | 0.77 | EPHX1 (0.50) | EPHX1CPN1CPB2ALOX15TSHR | |
| SCHEMBL8991906 | 0.73 | ALDH1A1 (0.42) | EPHX1ITGB3EPHX2 | |
| SCHEMBL21468160 | 0.73 | SMN1; SMN2 (0.41) | EPHX1TSHRITGB3 | |
| SCHEMBL27733842 | 0.73 | SMN1; SMN2 (0.41) | EPHX1TSHRITGB3 | |
| SCHEMBL1410684 | 0.73 | SMN1; SMN2 (0.41) | EPHX1TSHRITGB3 | |
| SCHEMBL3458110 | 0.73 | KMT2A (0.46) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053131-A1 | HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | CHROMA THERAPEUTICS LTD. (GB) | 2008-05-08 | — | — | WO | disclosed |