Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.36 |
| ▸ | GLRB | P48167 | 1/20 | 0.36 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16239320 | 0.96 | MEN1 (0.46) | MEN1KMT2ACA2CA1CYP1A2 | |
| SCHEMBL1046672 | 0.85 | MEN1 (0.42) | MEN1KMT2ACA2CA1CYP1A2 | |
| SCHEMBL14557207 | 0.81 | CYP2C19 (0.46) | MEN1KMT2ACA2CA1CYP1A2 | |
| SCHEMBL2789037 | 0.78 | GLRA3 (0.59) | MEN1KMT2ACA2CA1CYP1A2 | |
| SCHEMBL1046671 | 0.78 | MEN1 (0.44) | MEN1KMT2ACA2CA1CYP1A2 | |
| SCHEMBL11641750 | 0.77 | CYP2C19 (0.46) | MEN1KMT2ACA2CA1CYP1A2 | |
| SCHEMBL12057393 | 0.76 | MEN1 (0.61) | MEN1KMT2ACA2CA1CYP2C9 | |
| SCHEMBL1045816 | 0.76 | MEN1 (0.39) | MEN1KMT2ACA2CA1CYP1A2 | |
| SCHEMBL19296761 | 0.76 | ALDH1A1 (0.39) | MEN1KMT2ACA2CA1CYP1A2 | |
| SCHEMBL2790316 | 0.75 | GLRA3 (0.59) | MEN1KMT2ACA2CA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188657-A1 | CHEMICAL PROCESS | ASTRAZENECA UK LIMITED (GB) | 2008-08-07 | — | — | US | disclosed |
| WO-2008065410-A1 | PROCESS FOR THE PREPARATION OF ROSUVASTATIN | ASTRAZENECA UK LIMITED (GB) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188657-A1 | CHEMICAL PROCESS | HMGCR, CYP4A11, ACSL4 | MEN1 2050/4885KMT2A 3239/4885CA2 1892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.