Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 7/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535444 | 0.93 | CRHR1 (0.58) | CRHR1CASP3PAX8SENP8SENP7 | |
| SCHEMBL7626666 | 0.91 | CRHR1 (0.56) | CRHR1CASP3PAX8SENP8SENP7 | |
| SCHEMBL8204328 | 0.90 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL7534580 | 0.82 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL7618498 | 0.81 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL8204017 | 0.76 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL27516758 | 0.71 | CRHR1 (0.71) | CRHR1 | |
| SCHEMBL5866990 | 0.70 | CRHR1 (0.66) | CRHR1 | |
| SCHEMBL16606730 | 0.69 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL8204559 | 0.69 | CRHR1 (0.50) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107300-A | CORTICOTROPIN RELEASING FACTOR ANTAGONIST; PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS (US) | 2000-08-22 | — | — | US | disclosed |