Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 9/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 9/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.39 |
| ▸ | ITGAV | P06756 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818205 | 1.00 | MET (0.41) | METTGM2MTNR1AHCRTR1HCRTR2 | |
| SCHEMBL820565 | 0.88 | ERAP2 (0.43) | — | |
| SCHEMBL10109808 | 0.87 | MET (0.45) | METTGM2MTNR1ADRD2DRD4 | |
| SCHEMBL374971 | 0.87 | MET (0.45) | METTGM2MTNR1ADRD2DRD4 | |
| SCHEMBL820242 | 0.87 | MET (0.45) | METTGM2MTNR1ADRD2DRD4 | |
| SCHEMBL820247 | 0.87 | MET (0.45) | METTGM2MTNR1ADRD2DRD4 | |
| SCHEMBL820248 | 0.85 | BCHE (0.39) | METTGM2ITGB1ITGA5ITGB3 | |
| SCHEMBL379870 | 0.85 | BCHE (0.39) | METTGM2ITGB1ITGA5ITGB3 | |
| SCHEMBL13787023 | 0.85 | BCHE (0.39) | METTGM2ITGB1ITGA5ITGB3 | |
| SCHEMBL375113 | 0.82 | ELANE (0.38) | HCRTR1HCRTR2ITGB1ITGA5ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288116-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUITCAL CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110288116-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUITCAL CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| WO-2009094287-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUTICAL CORPORATION (US) | 2009-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288116-A1 | IAP INHIBITORS | XIAP, BIRC5, BIRC7 | MET 4492/4885TGM2 2575/4885MTNR1A 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.