Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206721 | 0.93 | SLC6A1 (0.61) | SLC6A1DRD2DRD4DRD3 | |
| SCHEMBL8206888 | 0.93 | SLC6A1 (0.61) | SLC6A1DRD2DRD4DRD3 | |
| SCHEMBL8202612 | 0.93 | SLC6A1 (0.61) | SLC6A1DRD2DRD4DRD3 | |
| SCHEMBL9085830 | 0.91 | SLC6A1 (0.74) | SLC6A1 | |
| SCHEMBL8202368 | 0.90 | SLC6A1 (0.57) | SLC6A1DRD2DRD4DRD3 | |
| SCHEMBL9083825 | 0.89 | SLC6A1 (0.68) | SLC6A1 | |
| SCHEMBL9086228 | 0.88 | SLC6A1 (0.69) | SLC6A1 | |
| SCHEMBL8204387 | 0.85 | SLC6A1 (0.52) | SLC6A1DRD2DRD4DRD3CYP3A4 | |
| SCHEMBL7843283 | 0.85 | SLC6A1 (0.52) | SLC6A1DRD2DRD4DRD3 | |
| SCHEMBL7843959 | 0.85 | SLC6A1 (0.52) | SLC6A1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738262-B1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK AS (DK) | 2000-04-19 | — | — | EP | claimed |