Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | DRD3 | P35462 | 4/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843283 | 1.00 | SLC6A1 (0.52) | SLC6A1HRH1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7838269 | 0.92 | HTR7 (0.51) | SLC6A1HRH1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8206721 | 0.91 | SLC6A1 (0.61) | SLC6A1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8202612 | 0.91 | SLC6A1 (0.61) | SLC6A1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8206888 | 0.89 | SLC6A1 (0.61) | SLC6A1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8202368 | 0.88 | SLC6A1 (0.57) | SLC6A1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7608377 | 0.85 | SLC6A1 (0.68) | SLC6A1HRH1 | |
| SCHEMBL7606372 | 0.85 | SLC6A1 (0.68) | SLC6A1HRH1 | |
| SCHEMBL9083825 | 0.85 | SLC6A1 (0.68) | SLC6A1 | |
| SCHEMBL7842305 | 0.85 | CHRNB2 (0.49) | HRH1CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820450-B1 | N-substituted azaheterocyclic carboxylic acids and alkylesters thereof | NOVO NORDISK AS (DK) | 2001-09-12 | — | — | EP | claimed |