SCHEMBL820254

SCHEMBL820254

O=C1NCCC(c2ccccc2)CCN1

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 2/20 0.63
SIGMAR1 Q99720 2/20 0.63
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 1/20 0.43
HTR6 P50406 1/20 0.43
SRD5A1 P18405 1/20 0.41
AKR1C3 P42330 1/20 0.40
AKR1C1 Q04828 1/20 0.40
NR3C1 P04150 2/20 0.40
HTR2C P28335 1/20 0.39
DDB1 Q16531 1/20 0.39
CRBN Q96SW2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4889595 0.82 SLC18A3 (0.57) SLC18A3SIGMAR1GAAMAPTSMN1; SMN2
SCHEMBL2937477 0.82 SLC18A3 (0.57) SLC18A3SIGMAR1GAAMAPTSMN1; SMN2
SCHEMBL1568261 0.80 SLC18A3 (0.53) SLC18A3SIGMAR1GAAMAPTHPGD
Benzene SCHEMBL28128069 0.78 SLC18A3 (1.00) SLC18A3SIGMAR1SMN1; SMN2HPGDKMT2A
SCHEMBL4574 0.78 SLC18A3 (1.00) SLC18A3SIGMAR1SMN1; SMN2HPGDKMT2A
SCHEMBL17117210 0.76 SMN1; SMN2 (0.41) SLC18A3SIGMAR1GAAMAPTSMN1; SMN2
Hydrochloric Acid SCHEMBL1481633 0.76 SLC18A3 (0.95) SLC18A3SIGMAR1SMN1; SMN2HPGDKMT2A
Hydrogen Sulfide SCHEMBL27710844 0.76 SLC18A3 (0.95) SLC18A3SIGMAR1SMN1; SMN2HPGDKMT2A
Piperazine SCHEMBL27350525 0.76 SLC18A3 (0.95) SLC18A3SIGMAR1SMN1; SMN2HPGDKMT2A
SCHEMBL7619610 0.75 SLC18A3 (0.57) SLC18A3SIGMAR1GAASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3947428-A BIS- OR TRIS-N,N-ETHYLENEUREA PROMOTER MITSUBOSHI BELTING LTD. (JA) 1976-03-30 US claimed
EP-1802697-B1 ADDITIVE PACKAGE FOR THERMOPLASTIC CONDENSATION POLYMERS DU PONT (US) 2011-07-20 EP disclosed
EP-2264095-A1 Additive package for thermoplastic condensation polymers E. I. du Pont de Nemours and Company (US) 2010-12-22 EP disclosed
US-7544387-B2 Additive package for thermoplastic condensation polymers THE CHEMOURS COMPANY FC, LLC 2009-06-09 US disclosed
US-20070299184-A1 Additive Package for Thermoplastic Condensation Polymers THE CHEMOURS COMPANY FC, LLC 2007-12-27 US disclosed
EP-1802697-A4 ADDITIVE PACKAGE FOR THERMOPLASTIC CONDENSATION POLYMERS DU PONT (US) 2007-10-24 EP disclosed
EP-1802697-A2 ADDITIVE PACKAGE FOR THERMOPLASTIC CONDENSATION POLYMERS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-07-04 EP disclosed
EP-1564235-B1 Biodegradable film NIPPON CATALYTIC CHEM IND (JP) 2007-04-11 EP disclosed
WO-2006045086-A2 ADDITIVE PACKAGE FOR THERMOPLASTIC CONDENSATION POLYMERS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-04-27 WO disclosed
US-20050182204-A1 Biodegradable film NIPPON SHOKUBAI CO., LTD. (JP) 2005-08-18 US disclosed
EP-1564235-A1 Biodegradable film NIPPON SHOKUBAI CO., LTD. (JP) 2005-08-17 EP disclosed
US-6730709-B2 HEATING, MELTING MIXTURE OF AROMATIC AND ALIPHATIC POLYESTER NIPPON SHOKUBAI CO., LTD. (JP) 2004-05-04 US disclosed
EP-0710685-B1 Process for producing aliphatic polyester NIPPON CATALYTIC CHEM IND (JP) 2004-01-21 EP disclosed
US-20020006973-A1 Biodegradable recycled polyester resin and production process therefor NIPPON SHOKUBAI CO., LTD. 2002-01-17 US disclosed
EP-1160269-A2 Biodegradable recycled polyester resin and production process therefor Nippon Shokubai Co., Ltd. (JP) 2001-12-05 EP disclosed
EP-1148074-A2 Process for producing aliphatic polyester NIPPON SHOKUBAI CO., LTD. (JP) 2001-10-24 EP disclosed
US-5843573-A Polyester resin composition NIPPON SHOKUBAI CO., LTD. (JP) 1998-12-01 US disclosed
US-5616681-A CARRYING OUT RING-OPENING POLYMERIZATION OF CYCLIC ACID ANHYDRIDE WITH CYCLIC ETHER IN PRESENCE OF ZIRCONIUM COMPOUND NIPPON SHOKUBAI CO., LTD. (JP) 1997-04-01 US disclosed
US-3947428-A BIS- OR TRIS-N,N-ETHYLENEUREA PROMOTER MITSUBOSHI BELTING LTD. (JA) 1976-03-30 US disclosed