Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937477 | 1.00 | SLC18A3 (0.57) | SLC18A3SIGMAR1DDB1CRBNSRD5A1 | |
| SCHEMBL1568261 | 0.83 | SLC18A3 (0.53) | SLC18A3SIGMAR1DDB1CRBNHPGD | |
| SCHEMBL2790425 | 0.83 | DDB1 (0.49) | SLC18A3SIGMAR1DDB1CRBNSRD5A1 | |
| SCHEMBL820254 | 0.82 | SLC18A3 (0.63) | SLC18A3SIGMAR1DDB1CRBNSRD5A1 | |
| SCHEMBL7619610 | 0.78 | SLC18A3 (0.57) | SLC18A3SIGMAR1SRD5A1HPGDGAA | |
| SCHEMBL14451372 | 0.77 | ESR2 (0.40) | DDB1CRBNGAAHTR6KMT2A | |
| Hydrochloric Acid SCHEMBL9482318 | 0.76 | ESR2 (0.59) | SLC18A3SIGMAR1DDB1CRBNSRD5A1 | |
| SCHEMBL76840 | 0.76 | ESR2 (0.63) | SLC18A3SIGMAR1DDB1CRBNSRD5A1 | |
| SCHEMBL1198558 | 0.74 | DDB1 (0.43) | SLC18A3SIGMAR1DDB1CRBNSRD5A1 | |
| Water SCHEMBL27808263 | 0.74 | ESR2 (0.61) | SLC18A3SIGMAR1DDB1CRBNSRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | PFIZER INC. | 2008-12-18 | — | — | US | disclosed |
| US-20080280933-A1 | BENZIMIDAZOLYL COMPOUNDS | EFREMOV IVAN | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280933-A1 | BENZIMIDAZOLYL COMPOUNDS | PAICS, TMBIM6, ABCG2 | SLC18A3 1341/4885SIGMAR1 2856/4885DDB1 4835/4885 |
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | AZI2, PAICS, UGT2B7 | SLC18A3 1289/4885SIGMAR1 2853/4885DDB1 4222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.