Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3752343 | 0.91 | GPBAR1 (0.36) | ALDH1A1L3MBTL1SCN9ARORCNPSR1 | |
| SCHEMBL3752748 | 0.80 | CTSA (0.38) | RORC | |
| SCHEMBL3753269 | 0.79 | MAPK10 (0.39) | ALDH1A1SCN9ARORCHPGDLMNA | |
| SCHEMBL3747394 | 0.79 | KMO (0.39) | RORCNPSR1KMT2AHPGDGPBAR1 | |
| SCHEMBL3757598 | 0.79 | ADORA2A (0.39) | ALDH1A1L3MBTL1NPSR1KMT2AHPGD | |
| SCHEMBL3753312 | 0.73 | ADORA2A (0.43) | ALDH1A1NPSR1SMN1; SMN2LMNAGAA | |
| SCHEMBL3752403 | 0.72 | ADORA2A (0.41) | NPSR1LMNA | |
| SCHEMBL3752534 | 0.72 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1SCN9ANPSR1MAPT | |
| SCHEMBL3749684 | 0.71 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1SCN9ARORCMAPT | |
| SCHEMBL3754265 | 0.71 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1RORCNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031501-A2 | 2-PHENOXY NICOTINE ACID DERIVATIVE AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-20 | — | — | WO | disclosed |