Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.45 |
| ▸ | PRCP | P42785 | 6/20 | 0.44 |
| ▸ | CCR2 | P41597 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8203440 | 0.91 | HTR2C (0.49) | HTR2CPRCPCCR1DRD2MCHR1 | |
| SCHEMBL8588802 | 0.86 | HTR2C (0.48) | HTR2CCCR2DRD2MCHR1LMNA | |
| SCHEMBL8200776 | 0.86 | HTR2C (0.45) | HTR2CPRCPCCR1DRD2MCHR1 | |
| SCHEMBL8200335 | 0.86 | HTR2C (0.45) | HTR2CPRCPCCR1DRD2MCHR1 | |
| SCHEMBL8200268 | 0.86 | HTR2C (0.46) | HTR2CPRCPCCR2NPC1RAB9A | |
| SCHEMBL8202809 | 0.85 | HTR2C (0.45) | HTR2CPRCPCCR2NAMPTDRD2 | |
| SCHEMBL8199972 | 0.84 | HTR2C (0.46) | HTR2CDRD2MCHR1 | |
| SCHEMBL8204772 | 0.84 | HTR2C (0.50) | HTR2CDRD2MCHR1 | |
| SCHEMBL8200324 | 0.84 | HTR2C (0.45) | HTR2CPRCPDRD2MCHR1LMNA | |
| SCHEMBL8589689 | 0.83 | HTR2C (0.44) | HTR2CPRCPCCR2DRD2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048877-A | Tetralone derivatives as antiarrhythmic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-04-11 | — | — | US | claimed |
| US-6048877-A | Tetralone derivatives as antiarrhythmic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-04-11 | — | — | US | disclosed |