Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 18/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12876207 | 0.86 | CACNA1H (0.68) | CACNA1H | |
| SCHEMBL8202719 | 0.75 | CACNA1H (0.63) | CACNA1HTRPV1 | |
| SCHEMBL8202012 | 0.73 | CACNA1H (0.51) | CACNA1HTRPV1 | |
| SCHEMBL8202765 | 0.73 | TRPV1 (0.46) | CACNA1HTRPV1 | |
| SCHEMBL8212825 | 0.73 | CACNA1H (0.55) | CACNA1H | |
| SCHEMBL12876238 | 0.71 | CACNA1H (0.58) | CACNA1H | |
| SCHEMBL14263480 | 0.70 | CACNA1H (0.61) | CACNA1HTRPV1 | |
| SCHEMBL13595860 | 0.69 | CACNA1H (0.83) | CACNA1H | |
| SCHEMBL14263481 | 0.67 | CACNA1H (0.63) | CACNA1HTRPV1 | |
| SCHEMBL8202128 | 0.67 | CACNA1H (0.47) | CACNA1HGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033464-A2 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF DISORDERS OF THE LIPID METABOLISM | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |