SCHEMBL8202812

SCHEMBL8202812

CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)OCc2ccccc2)Cc2ccc(cc2)OCCCC[C@@H](C=O)NC1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CAPN2 P17655 14/20 1.00
CTSB P07858 2/20 0.56
PSMB11 A5LHX3 1/20 0.56
PSMA7 O14818 1/20 0.56
CAPN1 P07384 1/20 0.56
PSMB1 P20618 1/20 0.56
PSMA1 P25786 1/20 0.56
PSMA2 P25787 1/20 0.56
PSMA3 P25788 1/20 0.56
PSMA4 P25789 1/20 0.56
PSMB8 P28062 1/20 0.56
PSMB9 P28065 1/20 0.56
PSMA5 P28066 1/20 0.56
PSMB4 P28070 1/20 0.56
PSMB6 P28072 1/20 0.56
PSMB5 P28074 1/20 0.56
PSMB10 P40306 1/20 0.56
PSMB3 P49720 1/20 0.56
PSMB2 P49721 1/20 0.56
PSMA6 P60900 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12943162 0.99 CAPN2 (1.00) CAPN2CTSBPSMB11PSMA7CAPN1
SCHEMBL8195187 0.93 CAPN2 (0.88) CAPN2CTSBPSMB11PSMA7CAPN1
SCHEMBL12943114 0.93 CAPN2 (0.86) CAPN2CTSBPSMB11PSMA7CAPN1
SCHEMBL12943083 0.90 CAPN2 (0.83) CAPN2CTSBPSMB11PSMA7CAPN1
SCHEMBL930942 0.90 CAPN2 (0.82) CAPN2CTSBPSMB11PSMA7CAPN1
SCHEMBL15869910 0.90 CAPN2 (0.82) CAPN2CTSBPSMB11PSMA7CAPN1
SCHEMBL12943166 0.90 CAPN2 (0.82) CAPN2CTSBPSMB11PSMA7CAPN1
SCHEMBL12943161 0.90 CAPN2 (0.84) CAPN2CTSBPSMB11PSMA7CAPN1
SCHEMBL8209264 0.90 CAPN2 (1.00) CAPN2CTSBPSMB11PSMA7CAPN1
SCHEMBL8208025 0.89 CAPN2 (1.00) CAPN2CTSBPSMB11PSMA7CAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-222380012-U Aeronautical electric control test system based on FPGA and CAN bus 成都能通科技股份有限公司 2025-01-21 CN claimed
CN-219287605-U Network hard disk video recorder system 珠海安士佳电子有限公司 2023-06-30 CN claimed
CN-217643407-U Industrial data image acquisition integrated transmission device 河北天遥航空设备科技有限公司 2022-10-21 CN claimed
CN-222380012-U Aeronautical electric control test system based on FPGA and CAN bus 成都能通科技股份有限公司 2025-01-21 CN disclosed
US-20240279710-A1 FLUORESCENT PROBES TOHOKU TECHNO ARCH CO., LTD. (JP) 2024-08-22 US disclosed
EP-4361166-A1 FLUORESCENT PROBES Tohoku Techno Arch Co., Ltd. (JP) 2024-05-01 EP disclosed
CN-219287605-U Network hard disk video recorder system 珠海安士佳电子有限公司 2023-06-30 CN disclosed
WO-2022270607-A1 FLUORESCENT PROBES 株式会社 東北テクノアーチ 2022-12-29 WO disclosed
CN-217643407-U Industrial data image acquisition integrated transmission device 河北天遥航空设备科技有限公司 2022-10-21 CN disclosed
CN-216122267-U Stepping motor control device 南京志良电子科技有限公司 2022-03-22 CN disclosed
CN-215934842-U Multifunctional broadband VPX receiving system 四川中芯微电电子科技有限责任公司 2022-03-01 CN disclosed
US-9434762-B2 Macrocyclic cysteine protease inhibitors and compositions thereof UNIVERSITY OF CANTERBURY (NZ) 2016-09-06 US disclosed
US-20140194362-A1 Macrocyclic Cysteine Protease Inhibitors and Compositions Thereof LINCOLN UNIVERSITY (NZ) 2014-07-10 US disclosed
US-20110021434-A1 Macrocyclic Cysteine Protease Inhibitors and Compositions Thereof UNIVERSITY OF CANTERBURY (NZ) 2011-01-27 US disclosed
WO-2008048121-A2 MACROCYCLIC CYSTEINE PROTEASE INHIBITORS AND COMPOSITIONS THEREOF LINCOLN UNIVERSITY (NZ) 2008-04-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240279710-A1 FLUORESCENT PROBES CAPN1, CAPN2, CAPNS1 CAPN2 2/4885CTSB 99/4885PSMB11 321/4885
US-20140194362-A1 Macrocyclic Cysteine Protease Inhibitors and Compositions Thereof CAPNS1, CAPN1, CAPN9 CAPN2 4/4885CTSB 11/4885PSMB11 171/4885
US-20110021434-A1 Macrocyclic Cysteine Protease Inhibitors and Compositions Thereof CAPNS1, CAPN1, CAPN9 CAPN2 4/4885CTSB 11/4885PSMB11 171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.