Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202862 | 1.00 | MEN1 (0.37) | MEN1KMT2ANPC1RAB9AGPR35 | |
| SCHEMBL6618504 | 0.76 | MEN1 (0.61) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8186775 | 0.73 | PTGS2 (0.42) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8186770 | 0.73 | PTGS2 (0.42) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL13017825 | 0.73 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9AGPR35 | |
| SCHEMBL8182128 | 0.73 | ALDH1A1 (0.57) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8182127 | 0.73 | ALDH1A1 (0.57) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8180274 | 0.71 | SIRT2 (0.56) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8180272 | 0.71 | SIRT2 (0.56) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8188189 | 0.70 | MEN1 (0.54) | MEN1KMT2ANPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018745-A1 | OXAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |