Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189695 | 0.92 | ADRB2 (0.36) | ADRB2ADRB1NR3C2 | |
| SCHEMBL8197296 | 0.88 | BRD4 (0.39) | ADRB2ADRB1NR3C2 | |
| SCHEMBL14079839 | 0.83 | ADRB2 (0.39) | ADRB2ADRB1NR3C2 | |
| SCHEMBL8190807 | 0.83 | MAPT (0.40) | NR3C2 | |
| SCHEMBL8206837 | 0.80 | NR3C2 (0.36) | ADRB2ADRB1NR3C2 | |
| SCHEMBL8196796 | 0.80 | NR3C2 (0.47) | ADRB2ADRB1NR3C2 | |
| SCHEMBL14080051 | 0.78 | IL4I1 (0.39) | ADRB2ADRB1NR3C2 | |
| SCHEMBL13181783 | 0.75 | PARP1 (0.37) | ADRB2ADRB1NR3C2 | |
| SCHEMBL13424803 | 0.75 | PARP1 (0.47) | ADRB2ADRB1NR3C2 | |
| SCHEMBL5215313 | 0.74 | NR3C2 (0.37) | ADRB2ADRB1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063668-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |