Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 17/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480974 | 0.93 | CRHR1 (0.45) | CRHR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8203092 | 0.82 | CRHR1 (0.58) | CRHR1MEN1KMT2A | |
| SCHEMBL21886413 | 0.80 | CRHR1 (0.58) | CRHR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL21886412 | 0.80 | CRHR1 (0.60) | CRHR1MEN1KMT2A | |
| SCHEMBL20733327 | 0.78 | CRHR1 (0.75) | CRHR1MEN1KMT2A | |
| SCHEMBL21886149 | 0.78 | CRHR1 (0.58) | CRHR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL21886163 | 0.78 | CRHR1 (0.52) | CRHR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL21886231 | 0.78 | CRHR1 (0.62) | CRHR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7537257 | 0.76 | MEN1 (0.48) | CRHR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8202582 | 0.75 | CRHR1 (0.48) | CRHR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107300-A | CORTICOTROPIN RELEASING FACTOR ANTAGONIST; PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS (US) | 2000-08-22 | — | — | US | disclosed |