Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 15/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21886412 | 0.90 | CRHR1 (0.60) | CRHR1MEN1KMT2A | |
| SCHEMBL20733327 | 0.89 | CRHR1 (0.75) | CRHR1MEN1KMT2A | |
| SCHEMBL21886413 | 0.89 | CRHR1 (0.58) | CRHR1MEN1KMT2A | |
| SCHEMBL21886149 | 0.89 | CRHR1 (0.58) | CRHR1MEN1KMT2A | |
| SCHEMBL27500001 | 0.88 | CRHR1 (0.48) | CRHR1MEN1KMT2A | |
| SCHEMBL7534738 | 0.87 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL7539896 | 0.86 | CRHR1 (0.50) | CRHR1MEN1KMT2A | |
| SCHEMBL8204710 | 0.84 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL21886163 | 0.83 | CRHR1 (0.52) | CRHR1MEN1KMT2A | |
| SCHEMBL8202970 | 0.82 | CRHR1 (0.47) | CRHR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107300-A | CORTICOTROPIN RELEASING FACTOR ANTAGONIST; PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS (US) | 2000-08-22 | — | — | US | disclosed |