Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2091596 | 0.86 | IDO1 (0.62) | APLNRALDH1A1CA2CA12CA1 | |
| SCHEMBL17616539 | 0.83 | APLNR (0.54) | APLNRALDH1A1CA2CA12CA1 | |
| SCHEMBL5998553 | 0.80 | APLNR (0.63) | APLNRALDH1A1CA2CA12CA1 | |
| SCHEMBL4003210 | 0.80 | APLNR (0.63) | APLNRALDH1A1CA2CA12CA1 | |
| SCHEMBL1046460 | 0.80 | APLNR (0.63) | APLNRALDH1A1CA2CA12CA1 | |
| SCHEMBL1613798 | 0.79 | APLNR (0.62) | APLNRALDH1A1CA2CA12CA1 | |
| SCHEMBL7003958 | 0.78 | CYP3A4 (0.48) | ALDH1A1MAPTHTR2AMEN1KMT2A | |
| SCHEMBL6995301 | 0.78 | CYP1A2 (0.54) | APLNRALDH1A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL28309457 | 0.78 | APLNR (0.53) | APLNRALDH1A1MAPTHDAC3HDAC1 | |
| SCHEMBL31172821 | 0.77 | APLNR (0.66) | APLNRALDH1A1CA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2622 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300932-A1 | CYCLIC PEPTIDES TARGETING ALPHA-4-BETA-7 INTEGRIN | ZEALAND PHARMA A/S (DK) | 2021-09-30 | — | — | US | claimed |
| US-11072616-B2 | Cyclic peptides targeting alpha-4-beta-7 integrin | UNIVERSITE DE MONTREAL (CA) | 2021-07-27 | — | — | US | claimed |
| CN-109810047-A | (R) synthetic method of the chiral intermediate of -3- Phenylpiperidine or/and (S) -3- Phenylpiperidine and Ni Lapani | 上海博邦医药科技有限公司 | 2019-05-28 | — | — | CN | claimed |
| US-8618286-B2 | Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity | NEURAXON, INC. (CA) | 2013-12-31 | — | — | US | claimed |
| US-8106043-B2 | Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity | NEURAXON, INC. (CA) | 2012-01-31 | — | — | US | claimed |
| US-20100305315-A1 | Process for the preparation of 2-(primary/secondary amino)hydrocarbyl)-carbamoyl-7-oxo-2,6-diaza-bicyclo [3.2.0.]heptane-6-sulfonic acid derivatives | BASILEA PHARMACEUTICA AG | 2010-12-02 | — | — | US | claimed |
| EP-2231670-A2 | PROCESS FOR THE PREPARATION OF 2-(PRIMARY/SECONDARY AMINO)HYDROCARBYL)- CARBAMOYL-7-OXO-2,6-DIAZA-BICYCLOÝ3.2.0.¨HEPTANE-6-SULFONIC ACID DERIVATIVES | Basilea Pharmaceutica AG (CH) | 2010-09-29 | — | — | EP | claimed |
| WO-2009071638-A2 | PROCESS FOR THE PREPARATION OF 2-(PRIMARY/SECONDARY AMINO)HYDROCARBYL)- CARBAMOYL-7-OXO-2,6-DIAZA-BICYCLO[3.2.0.]HEPTANE-6-SULFONIC ACID DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2009-06-11 | — | — | WO | claimed |
| EP-0946478-B1 | PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES AND HYDROXAMIC ACID COMPOUNDS | AVENTIS PHARMA INC (US) | 2007-02-14 | — | — | EP | claimed |
| EP-1674484-A2 | Process for the solid phase synthesis of aldehydes, ketones, oximes, amines and hydroxamic acid componds | Aventis Pharmaceuticals Products Inc. (US) | 2006-06-28 | — | — | EP | claimed |
| EP-0292806-B1 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1994-11-02 | — | — | EP | claimed |
| US-5352687-A | Hypotensive agents | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-04 | — | — | US | claimed |
| US-5276024-A | 3-substituted cephalosporins, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | claimed |
| EP-0229381-B1 | METHIONINE-SUBSTITUTED 1,4-DIHYDROPYRIDINES, PROCESS FOR THE PREPARATION AND THEIR USE | BAYER AG (DE) | 1990-05-30 | — | — | EP | claimed |
| EP-0362634-A2 | Basic dihydropyridines, process for their preparation and their use as intermediates | BAYER AG (DE) | 1990-04-11 | — | — | EP | claimed |
| US-4841042-A | Process for the preparation of carbapenem intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | claimed |
| US-4840946-A | Benzazolythio-carbapenem antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | claimed |
| US-4808622-A | ANTIHYPERTENSIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | claimed |
| EP-0268963-A1 | Benzazolylthio-carbapenem antibiotics | BAYER AG (DE) | 1988-06-01 | — | — | EP | claimed |
| EP-0195963-A1 | Process for the preparation of carbapenem intermediates | BAYER AG (DE) | 1986-10-01 | — | — | EP | claimed |